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1

ChemInform Abstract: Palladium-Catalyzed Mono-N-allylation of Unprotected Anthranilic Acids with Allylic Alcohols in Aqueous Media.

Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2012

File:

PDF, 55 KB

2012

2

Palladium-Catalyzed Benzylation of Unprotected Anthranilic Acids with Benzyl Alcohols in Water

Hikawa, Hidemasa, Yokoyama, Yuusaku

Journal:

Organic Letters

Year:

2011

Language:

english

File:

PDF, 825 KB

english, 2011

3

A phenotypic drug discovery study on thienodiazepine derivatives as inhibitors of T cell proliferation induced by CD28 co-stimulation leads to the discovery of a first bromodomain inhibitor

Endo, Junichi, Hikawa, Hidemasa, Hamada, Maiko, Ishibuchi, Seigo, Fujie, Naoto, Sugiyama, Naoki, Tanaka, Minoru, Kobayashi, Haruhito, Sugahara, Kunio, Oshita, Koichi, Iwata, Kazunori, Ooike, Shinsuke,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

4

Palladium-catalyzed dehydrative N-benzylation/C-H benzylation cascade of 2-morpholinoanilines on water

Hikawa, Hidemasa, Ichinose, Risa, Kikkawa, Shoko, Azumaya, Isao

Journal:

Green Chemistry

Year:

2018

Language:

english

File:

PDF, 863 KB

english, 2018

5

A Borrowing Hydrogen Strategy for Dehydrative Coupling of Aminoisoquinolines with Benzyl Alcohols in Water

Hikawa, Hidemasa, Tan, Rie, Tazawa, Aoi, Kikkawa, Shoko, Azumaya, Isao

Journal:

European Journal of Organic Chemistry

Year:

2019

Language:

english

File:

PDF, 2.13 MB

english, 2019

6

Chemoselective Palladium-Catalyzed Reaction in Aqueous Media: Selectivity in the Reaction of Haloanilines with 1,1-Dimethylallyl Alcohol

Yuusaku Yokoyama, Noriko Takagi, Hidemasa Hikawa, Satoru Kaneko, Natsume Tsubaki, Hiroaki Okuno

Journal:

Advanced Synthesis & Catalysis

Year:

2007

Language:

english

File:

PDF, 136 KB

english, 2007

7

ChemInform Abstract: A Short Synthesis of Optically Active γ,γ-Dimethylallyltryptophan (DMAT).

Hidemasa Hikawa, Yuusaku Yokoyama, Yasuoki Murakami

Journal:

Year:

2000

File:

PDF, 31 KB

2000

8

ChemInform Abstract: Does Water Suppress the Racemization and Decomposition of Amino Acids?

Yuusaku Yokoyama, Hidemasa Hikawa, Yasuoki Murakami

Journal:

Year:

2001

Language:

english

File:

PDF, 31 KB

english, 2001

9

Total Synthesis Without Protection: Three-Step Synthesis of Optically Active Clavicipitic Acids by a Biomimetic Route.

Yuusaku Yokoyama, Hidemasa Hikawa, Masaharu Mitsuhashi, Aki Uyama, Yasuhiro Hiroki, Yasuoki Murakami

Journal:

Year:

2004

File:

PDF, 179 KB

2004

10

ChemInform Abstract: Cross-Coupling Reaction on N-(3,5-Dibromo-2-pyridyl)piperazines: Regioselective Synthesis of 3,5-Disubstituted Pyridylpiperazines.

Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2011

Language:

english

File:

PDF, 47 KB

english, 2011

11

ChemInform Abstract: Convenient Synthesis of Chiral Tryptophan Derivatives Using Negishi Cross-Coupling.

Minoru Tanaka, Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2011

File:

PDF, 25 KB

2011

12

Total Synthesis without Protection: Three-Step Synthesis of Optically Active Clavicipitic Acids by a Biomimetic Route

Yuusaku Yokoyama, Hidemasa Hikawa, Masaharu Mitsuhashi, Aki Uyama, Yasuhiro Hiroki, Yasuoki Murakami

Journal:

European Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

13

Cross-coupling reaction on N-(3,5-dibromo-2-pyridyl)piperazines: regioselective synthesis of 3,5-disubstituted pyridylpiperazines

Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2010

Language:

english

File:

PDF, 592 KB

english, 2010

14

Syntheses without protection: a three-step synthesis of optically active clavicipitic acid by utilizing biomimetic synthesis of 4-bromotryptophan

Yuusaku Yokoyama, Hidemasa Hikawa, Masaharu Mitsuhashi, Aki Uyama, Yasuoki Murakami

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 239 KB

english, 1999

15

Convenient synthesis of chiral tryptophan derivatives using Negishi cross-coupling

Minoru Tanaka, Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2011

Language:

english

File:

PDF, 456 KB

english, 2011

16

ChemInform Abstract: Palladium-Catalyzed Benzylation of Unprotected Anthranilic Acids with Benzyl Alcohols in Water.

Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2012

File:

PDF, 42 KB

2012

17

ChemInform Abstract: Palladium-Catalyzed S-Benzylation of Unprotected Mercaptobenzoic Acid with Benzyl Alcohols in Water.

Hidemasa Hikawa, Yuusaku Yokoyama

Journal:

Year:

2012

File:

PDF, 38 KB

2012

18

Palladium-catalyzed mono-N-allylation of unprotected amino acids with 1,1-dimethylallyl alcohol in water

Hikawa, Hidemasa, Yokoyama, Yuusaku

Journal:

Organic & Biomolecular Chemistry

Year:

2011

Language:

english

File:

PDF, 217 KB

english, 2011

19

Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors

Tanaka, Minoru, Li, Xin, Hikawa, Hidemasa, Suzuki, Takafumi, Tsutsumi, Katsuhiko, Sato, Masashi, Takikawa, Osamu, Suzuki, Hideharu, Yokoyama, Yuusaku

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 733 KB

english, 2013

20

ChemInform Abstract: Pd-Catalyzed Benzylic C-H Amidation with Benzyl Alcohols in Water: A Strategy to Construct Quinazolinones.

Hikawa, Hidemasa, Ino, Yukari, Suzuki, Hideharu, Yokoyama, Yuusaku

Journal:

Year:

2012

File:

PDF, 29 KB

2012

21

Pd-Catalyzed Benzylic C–H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones

Hikawa, Hidemasa, Ino, Yukari, Suzuki, Hideharu, Yokoyama, Yuusaku

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 470 KB

english, 2012

22

Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water-Soluble Au(III)/TPPMS in Water

Hikawa, Hidemasa, Suzuki, Hideharu, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 953 KB

english, 2013

23

Au(III)/TPPMS-Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water

Hikawa, Hidemasa, Suzuki, Hideharu, Azumaya, Isao

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

24

Palladium-Catalyzed Mono- N -allylation of Unprotected Anthranilic Acids with Allylic Alcohols in Aqueous Media

Hikawa, Hidemasa, Yokoyama, Yuusaku

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

25

Mercaptobenzoic acid-palladium(0) complexes as active catalysts for S-benzylation with benzylic alcohols via (η 3 -benzyl)palladium( ii ) cations in water

Hikawa, Hidemasa, Azumaya, Isao

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

26

Palladium-catalyzed S-benzylation of unprotected mercaptobenzoic acid with benzyl alcohols in water

Hikawa, Hidemasa, Yokoyama, Yuusaku

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

27

Benzoyl methyl phosphate as an efficient reagent for the selective monobenzoylation of N-Bz-FTY720

Hikawa, Hidemasa, Hamada, Maiko, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2014

Language:

english

File:

PDF, 619 KB

english, 2014

28

Does water suppress the racemization and decomposition of amino acids?

Yokoyama, Yuusaku, Hikawa, Hidemasa, Murakami, Yasuoki

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

29

N -Benzylation/Benzylic CH Amidation Cascade by the (η 3 -Benzyl)palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3-Phenyl-3,4-dihydro- (2 H )-1,2,4-benzothiadiazine 1,1-Dioxides

Hikawa, Hidemasa, Matsuda, Naoya, Suzuki, Hideharu, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Advanced Synthesis & Catalysis

Year:

2013

Language:

english

File:

PDF, 432 KB

english, 2013

30

Palladium-Catalyzed Benzylic CH Benzylation via Bis-Benzylpalladium(II) Complexes in Water: An Effective Pathway for the Direct Construction of N -(1,2-Diphenylethyl)anilines

Hikawa, Hidemasa, Izumi, Kyoko, Ino, Yukari, Kikkawa, Shoko, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Advanced Synthesis & Catalysis

Year:

2015

Language:

english

File:

PDF, 754 KB

english, 2015

31

Direct use of allylic alcohols for palladium-catalyzed synthesis of 3-allylbenzo[b]thiophenes, benzofurans and indoles in aqueous media

Dhage, Yogesh Daulat, Shirai, Tsukasa, Arima, Miho, Nakazima, Arisa, Hikawa, Hidemasa, Taichi Kusakabe, Isao Azumaya, Takahashi, Keisuke, Kato, Keisuke

Journal:

Year:

2015

Language:

english

File:

PDF, 425 KB

english, 2015

32

Mechanistic Studies for Synthesis of Bis(indolyl)methanes: Pd-Catalyzed C–H Activation of Indole–Carboxylic Acids with Benzyl Alcohols in Water

Hikawa, Hidemasa, Suzuki, Hideharu, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2013

Language:

english

File:

PDF, 2.00 MB

english, 2013

33

A Short Synthesis of Optically Active γ,γ-Dimethylallyltryptophan (DMAT)

Hikawa, Hidemasa, Yokoyama, Yuusaku, Murakami, Yasuoki

Journal:

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

34

Direct substitution of benzylic alcohols with electron-deficient benzenethiols via π-benzylpalladium( ii ) in water

Hikawa, Hidemasa, Toyomoto, Mariko, Kikkawa, Shoko, Azumaya, Isao

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

35

ChemInform Abstract: N-Benzylation/Benzylic C-H Amidation Cascade by the (η 3 -Benzyl)palladium System in Aqueous Media: An Effective Pathway for the Direct Construction of 3-Phenyl-3,4-dihydro-(2H)-1,2,4-benzothiadiazine 1,1-Dioxides.

Hikawa, Hidemasa, Matsuda, Naoya, Suzuki, Hideharu, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2014

File:

PDF, 36 KB

2014

36

Borrowing Hydrogen Methodology for N-Benzylation using a π-Benzylpalladium System in Water

Hikawa, Hidemasa, Koike, Toshitaka, Izumi, Kyoko, Kikkawa, Shoko, Azumaya, Isao

Journal:

Advanced Synthesis & Catalysis

Year:

2016

Language:

english

File:

PDF, 689 KB

english, 2016

37

Direct Use of Benzylic Alcohols for Gold(III)-Catalyzed S -Benzylation of Mercaptobenzoic Acids in Water

Hikawa, Hidemasa, Tada, Ayaka, Kikkawa, Shoko, Azumaya, Isao

Journal:

Advanced Synthesis & Catalysis

Year:

2016

Language:

english

File:

PDF, 584 KB

english, 2016

38

ChemInform Abstract: Palladium-Catalyzed Benzylic C-H Benzylation via Bis-benzylpalladium(II) Complexes in Water: An Effective Pathway for the Direct Construction of N-(1,2-Diphenylethyl)anilines.

Hikawa, Hidemasa, Izumi, Kyoko, Ino, Yukari, Kikkawa, Shoko, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2015

File:

PDF, 20 KB

2015

39

Cationic palladium( ii )-catalyzed dehydrative nucleophilic substitutions of benzhydryl alcohols with electron-deficient benzenethiols in water

Hikawa, Hidemasa, Machino, Yumo, Toyomoto, Mariko, Kikkawa, Shoko, Azumaya, Isao

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 678 KB

english, 2016

40

A Radical Pathway for Direct Substitution of Benzyl Alcohols with Water-Soluble Copper Catalyst in Water

Hikawa, Hidemasa, Mori, Yuki, Kikkawa, Shoko, Azumaya, Isao

Journal:

Advanced Synthesis & Catalysis

Year:

2016

Language:

english

File:

PDF, 642 KB

english, 2016

41

ChemInform Abstract: Benzoyl Methyl Phosphate as an Efficient Reagent for the Selective Monobenzoylation of N-Bz-FTY720.

Hikawa, Hidemasa, Hamada, Maiko, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2015

File:

PDF, 16 KB

2015

42

ChemInform Abstract: Chemoselective Benzylation of Unprotected Anthranilic Acids with Benzhydryl Alcohols by Water-Soluble Au(III)/TPPMS in Water.

Hikawa, Hidemasa, Suzuki, Hideharu, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2013

File:

PDF, 41 KB

2013

43

ChemInform Abstract: Benzoyl Methyl Phosphates as Efficient Reagents in the One-Pot Tandem Approach for the Synthesis of 2-Phenylbenzimidazoles in Water.

Hikawa, Hidemasa, Imani, Maki, Suzuki, Hideharu, Yokoyama, Yuusaku, Azumaya, Isao

Journal:

Year:

2014

File:

PDF, 19 KB

2014

44

ChemInform Abstract: Direct Use of Allylic Alcohols for Palladium-Catalyzed Synthesis of 3-Allylbenzo[b]thiophenes, Benzofurans and Indoles in Aqueous Media.

Dhage, Yogesh Daulat, Shirai, Tsukasa, Arima, Miho, Nakazima, Arisa, Hikawa, Hidemasa, Taichi Kusakabe, Isao Azumaya, Takahashi, Keisuke, Kato, Keisuke

Journal:

Year:

2015

File:

PDF, 26 KB

2015

45

ChemInform Abstract: Direct Substitution of Benzylic Alcohols with Electron-Deficient Benzenethiols via π-Benzylpalladium(II) in Water.

Hikawa, Hidemasa, Toyomoto, Mariko, Kikkawa, Shoko, Azumaya, Isao

Journal:

Year:

2016

File:

PDF, 29 KB

2016

46

ChemInform Abstract: A Radical Pathway for Direct Substitution of Benzyl Alcohols with Water-Soluble Copper Catalyst in Water.

Hikawa, Hidemasa, Mori, Yuki, Kikkawa, Shoko, Azumaya, Isao

Journal:

Year:

2016

File:

PDF, 26 KB

2016

47

ChemInform Abstract: Au(III)/TPPMS-Catalyzed Benzylation of Indoles with Benzylic Alcohols in Water.

Hikawa, Hidemasa, Suzuki, Hideharu, Azumaya, Isao

Journal:

Year:

2014

File:

PDF, 34 KB

2014

48

ChemInform Abstract: Direct Use of Benzylic Alcohols for Gold(III)-Catalyzed S-Benzylation of Mercaptobenzoic Acids in Water.

Hikawa, Hidemasa, Tada, Ayaka, Kikkawa, Shoko, Azumaya, Isao

Journal:

Year:

2016

File:

PDF, 25 KB

2016

49

ChemInform Abstract: Borrowing Hydrogen Methodology for N-Benzylation Using a π-Benzylpalladium System in Water.

Hikawa, Hidemasa, Koike, Toshitaka, Izumi, Kyoko, Kikkawa, Shoko, Azumaya, Isao

Journal:

Year:

2016

File:

PDF, 30 KB

2016

50

Synthesis of VIP-Lipopeptide Using a New Linker to Modify Liposomes: Towards the Development of a Drug Delivery System for Active Targeting

Masaka, Toru, Matsuda, Takuya, Li, Yingpeng, Koide, Yuki, Takami, Akira, Yano, Kenji, Imai, Ryosuke, Ichihara, Risa, Yagi, Nobuhiro, Suzuki, Hideharu, Hikawa, Hidemasa, Terada, Katsuhide, Yokoyama, Yu

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2013

Language:

english

File:

PDF, 838 KB

english, 2013